• Pioneering Disease Selective Therapies
  • Makers of the Endoarterial Biopsy Catheter
  • Taking the Guesswork out of Medicine
  • Targeted Solutions for Serious Diseases

Our lead therapeutic candidate, CARSKNKDC (CAR) peptide, represents a new paradigm in targeted therapy. CAR preferentially homes to, and penetrates diseased tissue while selectively augmenting the efficacy of therapies. CAR can selectively boost drug effectiveness and reduce systemic side effects by enhancing the targeted uptake of co-administered therapeutics in preclinical models of pulmonary hypertension and triple-negative breast cancer. Additionally, CAR has shown promise in accelerating wound healing, enhancing gene therapy, ameliorating cachexia and in improving sepsis survival.

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Our first interventional product, the endoarterial biopsy catheter, is the world’s first interventional device to obtain a biopsy sample from the inner layers of an artery in a minimally invasive fashion. Endoarterial biopsies will better enable the diagnosis, monitoring, and treatment of vascular-based diseases, and provide the synergy to develop a wide range of products, services, and pharmaceuticals that target vascular-based diseases.

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Our molecular diagnostic products and services will provide molecular analysis of endoarterial biopsy samples and provide a comprehensive profile of a patient’s vascular disease. Performing transcriptional profiling of biopsies has long been a hallmark of modern cancer care. At VBS, we extend that paradigm to pulmonary vascular and other diseases.

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Vascular BioSciences Awarded $2 Million Phase II STTR Grant From NHLBI to Develop CAR Peptide as a Targeted Therapy for Pulmonary Hypertension Read more »

Vascular BioSciences Awarded Up To $2.3 Million Fast-Track STTR Grant From NHLBI To Develop CAR Peptide For Pulmonary Hypertension Read more »

VBS Announces Online Publication of Scientific Article Describing First Orally Available Disease Homing Peptide That Can Selectively Enhance the Effects of Co-Administered Drugs Read more »

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Our Mission

Vascular BioSciences was founded to develop products that enhance and prolong human life. At VBS, we develop disease solutions as if we were developing them for our own family – because that’s what every patient is, a member of someone’s family. We make interventional catheters to obtain endoarterial biopsies, provide molecular diagnostic solutions, and advance targeted therapies for the treatment of serious and debilitating diseases.
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